| Ingredient | Amount | % DV% Daily Value — how much of the recommended daily intake one serving provides, based on a 2,000 calorie diet. 100% = full daily need. Values over 100% are common for water-soluble vitamins (B, C) and generally safe. Values over 200% are highlighted. |
|---|---|---|
| Vitamin C | 90 mg | 100% |
| Thiamine | 0.9 mg | 75% |
| Riboflavin | 0.98 mg | 75% |
| Vitamin B6 | 1.7 mg | 100% |
| Biotin | 15 mcg | 50% |
| Replenish Energy Blend | 485 mg | — |
Other ingredients: Water, Natural Flavors, Citric Acid, Sucralose, Gum Arabic, Coconut Oil, Xanthan Gum, Potassium Sorbate, Alpha-Tocopherol
This score evaluates label quality — dosage disclosure, transparency, cleanliness of inactive ingredients, and formula composition. It does not measure clinical efficacy, bioavailability, or third-party testing. Read full methodology
Same category, higher SupplementScore. Based on dosage transparency, label cleanliness, and formula quality.
The research summaries below are about the ingredients in general, drawn from published studies that often use different doses, forms, and populations than this product. A "strong" evidence rating for an ingredient does not mean this product will produce that effect — studied doses may be significantly higher or lower than what is contained here. Always verify doses against the Supplement Facts table above.
Involved in neurotransmitter synthesis including serotonin and dopamine. Cofactor for over 100 enzyme reactions.
B6 is a cofactor in the transsulfuration pathway, converting homocysteine to cysteine. This is a separate pathway from the B12/folate remethylation route.
Supports immune cell function. Regular supplementation may modestly reduce cold duration, but does not prevent colds.
Potent water-soluble antioxidant that protects cells from oxidative damage.
Essential cofactor for enzymes involved in collagen production.
At 400mg/day (far above RDA of 1.3mg), riboflavin may reduce migraine frequency. Effect is dose-dependent and not expected at typical supplement doses.
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Alternatives are selected from the same category (Vitamin C) with a higher overall score. This is not a recommendation — always verify ingredients and dosages match your needs.
Limited evidence. May help in cases of biotin deficiency but most people get adequate amounts from diet.
Essential cofactor for carboxylases involved in gluconeogenesis, fatty acid synthesis, and amino acid catabolism.
Essential cofactor for pyruvate dehydrogenase and other enzymes in carbohydrate metabolism.