| Ingredient | Amount | % DV% Daily Value — how much of the recommended daily intake one serving provides, based on a 2,000 calorie diet. 100% = full daily need. Values over 100% are common for water-soluble vitamins (B, C) and generally safe. Values over 200% are highlighted. |
|---|---|---|
| Vitamin B6 | 6 mg | 353% |
| Folate | 1333 mcg DFE | 333% |
| Vitamin B12 | 2500 mcg | 104167% |
| Biotin | 100 mcg | 333% |
| Proprietary Energy Blend (Combination) | 2.75 mg | — |
Other ingredients: Mannitol, Crospovidone, Stearic Acid, Vegetable Cellulose, Natural and Artificial flavor, Contains Less Than 2% of
This score evaluates label quality — dosage disclosure, transparency, cleanliness of inactive ingredients, and formula composition. It does not measure clinical efficacy, bioavailability, or third-party testing. Read full methodology
The research summaries below are about the ingredients in general, drawn from published studies that often use different doses, forms, and populations than this product. A "strong" evidence rating for an ingredient does not mean this product will produce that effect — studied doses may be significantly higher or lower than what is contained here. Always verify doses against the Supplement Facts table above.
Adequate folate intake before and during early pregnancy reduces risk of neural tube defects. This is one of the most well-established findings in nutrition.
Essential cofactor for nucleotide synthesis and cell division.
Essential for red blood cell formation. Deficiency causes megaloblastic anemia, confirmed by decades of clinical evidence.
Involved in myelin synthesis and nerve function. Adequate B12 status supports neurological health, particularly in older adults and vegans.
Cofactor in energy production pathways, but supplementation only helps if deficient.
Involved in neurotransmitter synthesis including serotonin and dopamine. Cofactor for over 100 enzyme reactions.
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B6 is a cofactor in the transsulfuration pathway, converting homocysteine to cysteine. This is a separate pathway from the B12/folate remethylation route.
Limited evidence. May help in cases of biotin deficiency but most people get adequate amounts from diet.
Essential cofactor for carboxylases involved in gluconeogenesis, fatty acid synthesis, and amino acid catabolism.