Nicotinamide Adenine Dinucleotide

Also known as: vitamin b3, nicotinic acid, niacinamide, nicotinamide

Vitamin B3, essential for energy metabolism and DNA repair. Used therapeutically at high doses to improve cholesterol levels.

16mgRDARecommended Dietary Allowance — the daily intake sufficient for 97-98% of healthy adults. Set by the National Institutes of Health.

35mgUpper LimitTolerable Upper Intake Level (UL) — the maximum daily dose unlikely to cause adverse health effects. Exceeding this consistently may increase toxicity risk.

26ProductsNumber of supplements in our database that contain this ingredient.

2Health ClaimsNumber of researched health benefits associated with this ingredient, rated by evidence strength (strong/moderate/weak).

3Side EffectsNumber of documented side effects from clinical literature and adverse event reports.

Health Claims & Evidence

moderateSupports cholesterol levels

At pharmacological doses (1500-3000mg), niacin may improve HDL cholesterol. This effect is dose-dependent and not expected at typical supplement doses.

16 studies on PubMed

strongSupports energy metabolism

Essential coenzyme (NAD/NADP) in hundreds of metabolic reactions.

524 studies on PubMed

Related studies:Automatically retrieved from PubMed based on keyword matching. Some may not directly address the specific claim above.Cardiac Energy Metabolism in Heart Failure.Circ Res (2021) · PMID 33983836 NAD(+) metabolism and its roles in cellular processes during ageing.Nat Rev Mol Cell Biol (2021) · PMID 33353981 NAD(+) metabolism: pathophysiologic mechanisms and therapeutic potential.Signal Transduct Target Ther (2020) · PMID 33028824

Known Side Effects

flushing (nicotinic acid form)
itching
liver damage at very high doses

Drug Interactions

statins
blood pressure medications
diabetes medications

Always consult your healthcare provider before combining supplements with medications.

Health Claims & Evidence

Known Side Effects

Drug Interactions

Products Containing Nicotinamide Adenine Dinucleotide (26)