Melatonin, Synthetic

Also known as: n-acetyl-5-methoxytryptamine

Hormone naturally produced by the pineal gland that regulates sleep-wake cycles. Commonly supplemented for jet lag, insomnia, and sleep onset difficulties.

5ProductsNumber of supplements in our database that contain this ingredient.

2Health ClaimsNumber of researched health benefits associated with this ingredient, rated by evidence strength (strong/moderate/weak).

4Side EffectsNumber of documented side effects from clinical literature and adverse event reports.

Health Claims & Evidence

moderateImproves sleep onset

May help with sleep onset, particularly for jet lag and delayed sleep phase. Typical doses are 0.5-5mg. Not a sedative — works by signaling circadian rhythm.

0 studies on PubMed

moderateAntioxidant properties

Melatonin is a potent free radical scavenger with anti-inflammatory properties.

1 studies on PubMed

Related studies:Automatically retrieved from PubMed based on keyword matching. Some may not directly address the specific claim above.[Melatonin, synthetic analogs, and the sleep/wake rhythm].Rev Neurol (2009) · PMID 19263393