Ashwagandha root standardized extract

Also known as: withania somnifera, indian ginseng, ksm-66, sensoril

Adaptogenic herb (Withania somnifera) used in Ayurvedic medicine for thousands of years. Helps body manage stress by modulating cortisol and supporting adrenal function.

2ProductsNumber of supplements in our database that contain this ingredient.

3Health ClaimsNumber of researched health benefits associated with this ingredient, rated by evidence strength (strong/moderate/weak).

4Side EffectsNumber of documented side effects from clinical literature and adverse event reports.

Health Claims & Evidence

strongReduces stress and anxiety

Multiple RCTs show cortisol reduction and improved stress/anxiety scores, primarily with standardized extracts (KSM-66, Sensoril) at 300-600mg/day.

8 studies on PubMed

Related studies:Automatically retrieved from PubMed based on keyword matching. Some may not directly address the specific claim above.A standardized Ashwagandha root extract alleviates stress, anxiety, and improves quality of life in healthy adults by modulating stress hormones: Results from a randomized, double-blind, placebo-controlled study.Medicine (Baltimore) (2023) · PMID 37832082 Body Weight Management in Adults Under Chronic Stress Through Treatment With Ashwagandha Root Extract: A Double-Blind, Randomized, Placebo-Controlled Trial.J Evid Based Complementary Altern Med (2017) · PMID 27055824 Safety and clinical effectiveness of Withania Somnifera (Linn.) Dunal root in human ailments.J Ethnopharmacol (2020) · PMID 32201301

moderateMay improve testosterone

Limited evidence for testosterone effects, primarily in stressed or subfertile men using KSM-66 extract. Results in healthy men are inconsistent.

1 studies on PubMed

Related studies:Automatically retrieved from PubMed based on keyword matching. Some may not directly address the specific claim above.Exploring the efficacy and safety of a novel standardized ashwagandha (Withania somnifera) root extract (Witholytin®) in adults experiencing high stress and fatigue in a randomized, double-blind, placebo-controlled trial.J Psychopharmacol (2023) · PMID 37740662

moderateSupports athletic performance

May improve VO2 max, strength, and recovery. Typically studied at 300-600mg/day of standardized root extract (KSM-66 or equivalent).

3 studies on PubMed

Related studies:Automatically retrieved from PubMed based on keyword matching. Some may not directly address the specific claim above.Effects of Ashwagandha ( Withania somnifera) standardized root extract on physical endurance and VO (2max) in healthy adults performing resistance training: An eight-week, prospective, randomized, double-blind, placebo-controlled study.F1000Res (2023) · PMID 38988644 Selected herbals and human exercise performance.Am J Clin Nutr (2000) · PMID 10919969 Effects of an Aqueous Extract of Withania somnifera on Strength Training Adaptations and Recovery: The STAR Trial.Nutrients (2018) · PMID 30463324

Known Side Effects

drowsiness
upset stomach
thyroid hormone changes
not safe during pregnancy

Drug Interactions

thyroid medications
immunosuppressants
sedatives
blood sugar medications

Always consult your healthcare provider before combining supplements with medications.

Products Containing Ashwagandha root standardized extract (2)

Highland LaboratoriesAdrenal Boost

77 2

Mt. Angel VitaminsAdrenal Support