Which Supplement Brands Have the Cleanest Labels?
We analyzed 116,409 supplement products from 5,790 brands and scored each product's formulation cleanliness — penalizing artificial colors, sweeteners, titanium dioxide, and other unnecessary additives. Here are the brands that consistently come out on top.
Top 10 Cleanest Brands (20+ products)
Brands with perfect 25/25 cleanliness across their entire product line:
- Eu Natural — 35 products, avg overall score 80.9
- Biotivia — 24 products, avg 80.9
- Emerald — 54 products, avg 80.8
- Signature Supplements — 107 products, avg 80.7
- Materia Organica — 29 products, avg 80.3
- Garden of Life MyKind Organics — 73 products, avg 80.2
- Codeage — 133 products, avg 80.1
- Herb Pharm Professional — 27 products, avg 80.0
- LuZa Beyond — 20 products, avg 80.0
- TumoRx — 30 products, avg 80.0
These brands use zero tier-1 and tier-2 fillers across all their products. Their "Other Ingredients" lists contain only necessary formulation components like cellulose, vegetable capsules, and rice flour.
What Makes a "Clean" Label?
In our scoring system, cleanliness starts at 25 points and deducts for each problematic additive found in the Other Ingredients list. Products lose 6 points for severe additives (titanium dioxide, artificial colors, sucralose) and 3 points for questionable ones (magnesium stearate, silicon dioxide, maltodextrin). Bonuses are given for Vegan, Organic, and Gluten Free certifications on the label.
A perfect 25/25 means zero unnecessary additives — only the minimum required for the supplement form (capsule shell, binding agent, etc.).
Browse by Brand
Explore all 5,790 brands in our database on the brands page, or filter supplements by score 80+ to find the cleanest products across all categories.
Data source: NIH DSLD. Full methodology.